Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | USP14 | P54578 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904066 | 0.78 | TRPV4 (0.38) | TRPV4ALDH1A1ARUSP14PGR | |
| SCHEMBL8903852 | 0.74 | TRPV4 (0.37) | TRPV4ALDH1A1ARUSP14PGR | |
| SCHEMBL6103578 | 0.72 | USP14 (0.38) | TRPV4ALDH1A1ARUSP14KDM1A | |
| SCHEMBL6103445 | 0.71 | DHODH (0.42) | TRPV4 | |
| SCHEMBL7697079 | 0.71 | USP14 (0.37) | TRPV4USP14 | |
| SCHEMBL29816521 | 0.71 | DHODH (0.43) | — | |
| SCHEMBL20108209 | 0.71 | DHODH (0.43) | — | |
| SCHEMBL8193759 | 0.70 | BCAT2 (0.40) | TRPV4ARUSP14 | |
| SCHEMBL20108199 | 0.70 | DHODH (0.44) | — | |
| SCHEMBL9126592 | 0.70 | L3MBTL1 (0.35) | TRPV4KDM1ABACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997026248-A1 | SUBSTITUTED N-ARYL NITROGEN HETEROCYCLIC COMPOUNDS AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-24 | — | — | WO | disclosed |