Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.61 |
| ▸ | TLR2 | O60603 | 1/20 | 0.61 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.61 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.61 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TFEB | P19484 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1852521 | 0.86 | ERN1 (0.47) | ERN1TLR2TLR1TLR6SRC | |
| SCHEMBL9995628 | 0.82 | NFE2L2 (0.50) | ERN1TLR2TLR1TLR6LMNA | |
| SCHEMBL15263272 | 0.82 | NFE2L2 (0.50) | ERN1TLR2TLR1TLR6LMNA | |
| SCHEMBL2843121 | 0.82 | ALDH1A1 (0.50) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL29850639 | 0.80 | ERN1 (0.56) | ERN1TLR2TLR1TLR6SRC | |
| SCHEMBL172698 | 0.80 | NFE2L2 (0.47) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL16955437 | 0.80 | NFE2L2 (0.47) | ERN1TLR2TLR1TLR6SRC | |
| SCHEMBL12283962 | 0.79 | ERN1 (0.43) | ERN1TLR2TLR1TLR6SRC | |
| SCHEMBL1579244 | 0.79 | ALDH1A1 (0.48) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL738533 | 0.79 | ERN1 (0.66) | ERN1TLR2TLR1TLR6SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 477 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143598-B | High-entropy carbon quantum dot nanomaterial and preparation method and application thereof | 中南大学 | 2024-11-08 | — | — | CN | claimed |
| CN-117143598-A | High-entropy carbon quantum dot nanomaterial and preparation method and application thereof | 中南大学 | 2023-12-01 | — | — | CN | claimed |
| CN-115092909-B | High-concentration fluorine-doped carbon dot and preparation method thereof | 中南大学 | 2023-06-09 | — | — | CN | claimed |
| CN-115092909-A | High-concentration fluorine-doped carbon dot and preparation method thereof | 中南大学 | 2022-09-23 | — | — | CN | claimed |
| CN-105254652-A | PROCESS FOR THE SELECTIVE DEPROTONATION AND FUNCTIONALIZATION OF 1-FLUORO-2-SUBSTITUTED-3-CHLOROBENZENES | DOW AGROSCIENCES LLC | 2016-01-20 | — | — | CN | claimed |
| EP-4680239-A2 | SIGMA-1 RECEPTOR ANTAGONISTS AND THEIR APPLICATIONS | Humanwell Pharmaceutical US, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| US-20250368605-A1 | Novel Substituted 6,7-Dihydro-5H-Benzo[7]Annulene Compounds, Processes for their Preparation and Therapeutic Uses Thereof | SANOFI (FR) | 2025-12-04 | — | — | US | disclosed |
| EP-4051680-B1 | CONDENSED BI-HETEROCYCLES AS INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | BIOGEN MA INC (US) | 2025-09-03 | — | — | EP | disclosed |
| US-20250268854-A1 | 2-AMINO-5,5-DIMETHYLHEXANOIC ACID DERIVATIVES AS SORTILIN MODULATORS FOR USE IN THE TREATMENT OF DISEASE OF THE CENTRAL NERVOUS SYSTEM | VESPER BIO APS (DK) | 2025-08-28 | — | — | US | disclosed |
| US-12391697-B2 | Condensed bi-heterocycles as inhibiting agents for Bruton's tyrosine kinase | BIOGEN MA INC. (US) | 2025-08-19 | — | — | US | disclosed |
| US-12221441-B2 | Plasma kallikrein inhibitors and uses thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-02-11 | — | — | US | disclosed |
| EP-4477220-A2 | PLASMA KALLIKREIN INHIBITORS AND USES THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2024-12-18 | — | — | EP | disclosed |
| WO-2005023800-A1 | HALO SUBSTITUTED BENZO`B! THIOPHENES WITH PI3K INHIBITORY ACTIVITY AS THERAPEUTIC AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-17 | — | — | WO | disclosed |
| WO-2004052847-A2 | TRICYCLIC STEROID HORMONE NUCLEAR RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |
| WO-2004043904-A1 | 3-ARYLOXY/THIO-3-SUBSTITUTED PROPANAMINES AND THEIR USE IN INHIBITING SEROTONIN AND NOREPHINEPHRINE REUPTAKE | ELI LILLY AND COMPANY (US) | 2004-05-27 | — | — | WO | disclosed |
| WO-2004043903-A1 | 3-ARYLOXY/ THIO-2, 3-SUBSTITUTED PROPANAMINES AND THEIR USE IN INHIBITING SEROTONIN AND NOREPINEPHRINE REUPTAKE | ELI LILLY AND COMPANY (US) | 2004-05-27 | — | — | WO | disclosed |
| WO-2004043931-A1 | PROPANAMINE DERIVATIVES AS SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITORS | ELI LILLY AND COMPANY (US) | 2004-05-27 | — | — | WO | disclosed |
| CN-1093536-C | 5-lipoxygenase inhibitors | PFIZER (US) | 2002-10-30 | — | — | CN | disclosed |
| WO-1998024740-A1 | FLUORINATION OF CARBONYL-SUBSTITUTED AROMATIC COMPOUNDS | F2 CHEMICALS LIMITED (GB) | 1998-06-11 | — | — | WO | disclosed |
| CN-1169722-A | 5-lipoxygenase inhibitors | PFIZER (US) | 1998-01-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250268854-A1 | 2-AMINO-5,5-DIMETHYLHEXANOIC ACID DERIVATIVES AS SORTILIN MODULATORS FOR USE IN THE TREATMENT OF DISEASE OF THE CENTRAL NERVOUS SYSTEM | SORT1, NMUR2, NMUR1 | ERN1 4514/4885TLR2 242/4885TLR1 671/4885 |
| US-20250368605-A1 | Novel Substituted 6,7-Dihydro-5H-Benzo[7]Annulene Compounds, Processes for their Preparation and Therapeutic Uses Thereof | CYP19A1, ESR1, ESR2 | ERN1 1383/4885TLR2 1249/4885TLR1 1937/4885 |
| US-12221441-B2 | Plasma kallikrein inhibitors and uses thereof | KLKB1, KLK1, KLK5 | ERN1 1116/4885TLR2 4618/4885TLR1 4718/4885 |
| US-12391697-B2 | Condensed bi-heterocycles as inhibiting agents for Bruton's tyrosine kinase | ABL1, CDK1, CDK2 | ERN1 780/4885TLR2 4147/4885TLR1 4071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.