Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895202 | 0.86 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1AKT1KDM4E | |
| SCHEMBL3046145 | 0.86 | KMT2A (0.48) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL3050396 | 0.83 | KMT2A (0.49) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL8896038 | 0.81 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1AKT1KDM4E | |
| SCHEMBL8893220 | 0.80 | ALDH1A1 (0.33) | MEN1KMT2AALDH1A1AKT1KDM4E | |
| SCHEMBL6363897 | 0.76 | AKT1 (0.48) | MEN1KMT2AALDH1A1AKT1ATM | |
| SCHEMBL8708141 | 0.75 | ALDH1A1 (0.36) | ALDH1A1ATMKLK5CTSLCTSB | |
| SCHEMBL17761773 | 0.75 | CTSL (0.45) | ALDH1A1AKT1KDM4EATMHCRTR1 | |
| SCHEMBL27496551 | 0.75 | AKT1 (0.45) | ALDH1A1AKT1KDM4EATMADRA2B | |
| SCHEMBL27529666 | 0.75 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624897-A | PARASITICIDES, NEMATOSIDES OF CYCLIC PEPTIDE LACTONES FOR VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |