Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894248 | 0.87 | ALDH1A1 (0.32) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL8895474 | 0.86 | MEN1 (0.43) | ALDH1A1AKT1KDM4EATMRIPK1 | |
| SCHEMBL8894581 | 0.84 | MEN1 (0.42) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL8707554 | 0.82 | CTSL (0.39) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL8896038 | 0.79 | ALDH1A1 (0.34) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL8895198 | 0.78 | AKT1 (0.39) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL8893220 | 0.78 | ALDH1A1 (0.33) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL5564821 | 0.77 | LMNA (0.51) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL7781713 | 0.77 | LMNA (0.51) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL5564818 | 0.77 | LMNA (0.51) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624897-A | PARASITICIDES, NEMATOSIDES OF CYCLIC PEPTIDE LACTONES FOR VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |