Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628814 | 0.86 | CASR (0.55) | RAB9ASMN1; SMN2NPC1MAPTKMT2A | |
| SCHEMBL8625971 | 0.86 | ALDH1A1 (0.52) | NAMPTMAPTNPSR1ALDH1A1CA1 | |
| SCHEMBL1543828 | 0.85 | RAB9A (0.67) | NAMPTRAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL8628472 | 0.81 | EPHX2 (0.55) | SMN1; SMN2MAPTCA1CA2LMNA | |
| SCHEMBL6688173 | 0.80 | TP53 (0.65) | NAMPTRAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL6688636 | 0.80 | NAMPT (0.64) | NAMPTRAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL31617997 | 0.80 | EPHX1 (0.58) | SMN1; SMN2CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL16588346 | 0.79 | KMT2A (0.55) | RAB9ASMN1; SMN2NPC1HPGDMAPT | |
| SCHEMBL3015738 | 0.78 | CYP4F2 (0.57) | NAMPTRAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL12993342 | 0.78 | RAB9A (0.60) | RAB9ACYP1A2CYP2C9HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703050-A | INHIBIT PLATELET AGGREGATION, METASTASIS OF CARCINOMA CELLS, OSTEOCLAST BINDING TO BONE SURFACE | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |