Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628472 | 0.88 | EPHX2 (0.55) | GAACA1CA2EPHX2PAX8 | |
| SCHEMBL8897098 | 0.86 | NAMPT (0.56) | ALDH1A1CA1CA2EPHX2MAPT | |
| SCHEMBL8628814 | 0.81 | CASR (0.55) | CA1CA2EPHX2PAX8CCNC | |
| SCHEMBL23782597 | 0.79 | PDE5A (0.45) | EPHX2 | |
| SCHEMBL30176194 | 0.79 | PDE5A (0.45) | EPHX2 | |
| SCHEMBL781885 | 0.79 | ALDH1A1 (0.62) | ALDH1A1CA2EPHX2PAX8PTPN7 | |
| SCHEMBL16152246 | 0.79 | SMN1; SMN2 (0.60) | ALDH1A1GAACA1CA2MAPT | |
| SCHEMBL9339394 | 0.78 | CA1 (0.51) | GAACA1CA2PAX8MAPT | |
| SCHEMBL8898134 | 0.78 | GAA (0.43) | ALDH1A1GAAEPHX2PAX8PTPN7 | |
| SCHEMBL8898154 | 0.78 | GAA (0.42) | ALDH1A1GAAEPHX2PAX8PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0689549-B1 | NEW UREA DERIVATES, THEIR PREPARATION AND THEIR USE | HOECHST AG (DE) | 1998-06-17 | — | — | EP | disclosed |
| US-5703050-A | INHIBIT PLATELET AGGREGATION, METASTASIS OF CARCINOMA CELLS, OSTEOCLAST BINDING TO BONE SURFACE | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |
| EP-0689549-A1 | NEW UREA DERIVATES, THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-03 | — | — | EP | disclosed |
| WO-1994022907-A1 | NEW UREA DERIVATES, THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |