Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10423913 | 0.86 | AKT1 (0.42) | LMNACHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL7332333 | 0.78 | RIPK1 (0.51) | LMNARIPK1CHRNB2CHRNA4CYP3A4 | |
| SCHEMBL5890773 | 0.76 | RIPK1 (0.63) | LMNARIPK1CHRNB2CHRNA4CYP3A4 | |
| SCHEMBL10424675 | 0.76 | L3MBTL1 (0.40) | — | |
| SCHEMBL5784249 | 0.75 | KDM4E (0.46) | LMNARIPK1CHRNB2CHRNA4CYP3A4 | |
| SCHEMBL7324763 | 0.72 | SSTR4 (0.52) | LMNARIPK1CHRNB2CHRNA4CYP3A4 | |
| SCHEMBL27875045 | 0.72 | KMT2A (0.48) | LMNARIPK1CHRNB2CHRNA4CYP3A4 | |
| SCHEMBL1737432 | 0.71 | AKT1 (0.42) | LMNARIPK1CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL13947717 | 0.71 | CHRNA7 (0.54) | LMNARIPK1CHRNB2CHRNA4TBXAS1 | |
| SCHEMBL20162475 | 0.71 | LTA4H (0.44) | LMNASLC1A5CYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587110-B1 | Condensed heterocyclic derivatives and agricultural or horticultural fungicides containing the same | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1997-12-17 | — | — | EP | disclosed |