Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899522 | 0.86 | RXFP1 (0.43) | HSD11B1TP53IDH1HTTKDM4E | |
| SCHEMBL8898917 | 0.76 | KMT2A (0.48) | KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL12320518 | 0.74 | KIF11 (0.36) | — | |
| SCHEMBL12320558 | 0.74 | KIF11 (0.36) | — | |
| SCHEMBL28365266 | 0.73 | TDP2 (0.47) | MAT2AL3MBTL1LMNA | |
| SCHEMBL30790937 | 0.73 | KDM4E (0.42) | KDM4EPDK2 | |
| SCHEMBL10222171 | 0.73 | PSMB8 (0.42) | PSMB8HSD11B1MAT2ACDC7CDK2 | |
| SCHEMBL8899305 | 0.72 | PSMB8 (0.41) | PSMB8HSD11B1MAT2ACDC7CDK2 | |
| SCHEMBL1605081 | 0.70 | FYN (0.41) | IDH1HTTLMNA | |
| SCHEMBL12320516 | 0.69 | CYP2A6 (0.35) | HSD11B1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143636-A | Indoles as insecticides and acaricides | AMERICAN CYANAMID CO (US) | 1997-02-26 | — | — | CN | disclosed |
| US-5599832-A | INDOLES SUBSTITUTED WITH GROUPS BOTH ELECTRON WITHDRAWING AND LIPOPHILIC; GROWING, HARVESTING AND STORAGE OF CROPS | AMERICAN CYANAMID COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| US-5502071-A | PLANTS | AMERICAN CYANAMID COMPANY (US) | 1996-03-26 | — | — | US | disclosed |
| EP-0697172-A1 | Indoles as insecticides and acaricides | AMERICAN CYANAMID COMPANY (US) | 1996-02-21 | — | — | EP | disclosed |