Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 5/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897533 | 0.86 | PSMB8 (0.38) | IDH1KDM4EHCRTR1MAPTCASP1 | |
| SCHEMBL16595667 | 0.81 | RXFP1 (0.47) | RXFP1MEN1KMT2AAHRKDM4E | |
| SCHEMBL31435622 | 0.79 | MCL1 (0.50) | MEN1KMT2AKDM4EMAPTTP53 | |
| SCHEMBL20799414 | 0.78 | RXFP1 (0.47) | RXFP1MEN1KMT2AAHRPHGDH | |
| SCHEMBL1115437 | 0.76 | BRPF1 (0.38) | RXFP1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL12900640 | 0.76 | KDM4E (0.31) | RXFP1KDM4EMAPT | |
| SCHEMBL3386079 | 0.76 | RXFP1 (0.46) | RXFP1MEN1KMT2AAHRKDM4E | |
| SCHEMBL8898917 | 0.76 | KMT2A (0.48) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL16595666 | 0.75 | LMNA (0.47) | RXFP1MEN1KMT2AAHRKDM4E | |
| SCHEMBL1113031 | 0.75 | XDH (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143636-A | Indoles as insecticides and acaricides | AMERICAN CYANAMID CO (US) | 1997-02-26 | — | — | CN | disclosed |
| US-5599832-A | INDOLES SUBSTITUTED WITH GROUPS BOTH ELECTRON WITHDRAWING AND LIPOPHILIC; GROWING, HARVESTING AND STORAGE OF CROPS | AMERICAN CYANAMID COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| US-5502071-A | PLANTS | AMERICAN CYANAMID COMPANY (US) | 1996-03-26 | — | — | US | disclosed |
| EP-0697172-A1 | Indoles as insecticides and acaricides | AMERICAN CYANAMID COMPANY (US) | 1996-02-21 | — | — | EP | disclosed |