Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | PDE9A | O76083 | 18/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13889499 | 0.83 | TK2 (0.40) | CDK4CCND1PDE9APDE1CPDE1B | |
| SCHEMBL12601708 | 0.83 | TK2 (0.40) | CDK4CCND1PDE9APDE1CPDE1B | |
| SCHEMBL889780 | 0.79 | CDK4 (0.35) | CDK4CCND1PDE9APDE1CPDE1B | |
| SCHEMBL889896 | 0.77 | CDK4 (0.34) | CDK4CCND1PDE9APDE1CPDE1B | |
| SCHEMBL23786492 | 0.71 | ADRB1 (0.47) | — | |
| SCHEMBL12123502 | 0.71 | ADRB1 (0.47) | — | |
| SCHEMBL889695 | 0.71 | ADRB1 (0.47) | — | |
| SCHEMBL14570606 | 0.71 | ADRB1 (0.47) | — | |
| SCHEMBL14771558 | 0.69 | PDE9A (0.66) | PDE9APDE1C | |
| SCHEMBL13889498 | 0.69 | PDE9A (0.34) | CDK4CCND1PDE9APDE1CPDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431366-B2 | Modified oligonucleotides and applications thereof | APPLIED BIOSYSTEMS, LLC (US) | 2013-04-30 | — | — | US | disclosed |
| US-20110287431-A1 | MODIFIED OLIGONUCLEOTIDES AND APPLICATIONS THEREOF | Life Technologies Corporation (US) | 2011-11-24 | — | — | US | disclosed |