Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23728205 | 0.84 | HPGD (0.54) | SMN1; SMN2ALDH1A1LMNAHPGDTSHR | |
| SCHEMBL1425482 | 0.84 | HPGD (0.58) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8898022 | 0.83 | L3MBTL1 (0.64) | SMN1; SMN2HTTALDH1A1LMNAHPGD | |
| SCHEMBL8896530 | 0.80 | ALDH1A1 (0.58) | SMN1; SMN2HTTALDH1A1LMNAMAPT | |
| SCHEMBL8898560 | 0.80 | POLB (0.55) | ALDH1A1MAPTPOLBHPGDNPSR1 | |
| SCHEMBL14405008 | 0.80 | HTT (0.46) | HTTALDH1A1LMNAHRH3 | |
| SCHEMBL5650248 | 0.80 | HTT (0.46) | HTTALDH1A1LMNAHRH3 | |
| SCHEMBL4185130 | 0.80 | HTT (0.46) | HTTALDH1A1LMNAHRH3 | |
| SCHEMBL12424630 | 0.79 | POLB (0.74) | ALDH1A1MAPTPOLBHPGDRAB9A | |
| SCHEMBL17676780 | 0.79 | ALDH1A1 (0.46) | SMN1; SMN2HTTRECQLALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |