Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1425482 | 0.86 | HPGD (0.58) | ALDH1A1LMNAMAPTKCNJ1SMN1; SMN2 | |
| SCHEMBL23728205 | 0.86 | HPGD (0.54) | ALDH1A1LMNAKCNJ1SMN1; SMN2 | |
| SCHEMBL4186870 | 0.86 | LMNA (0.65) | ALDH1A1LMNAMAPTKCNJ1SMN1; SMN2 | |
| SCHEMBL4431573 | 0.83 | MEN1 (0.57) | ALDH1A1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8898022 | 0.82 | L3MBTL1 (0.64) | ALDH1A1LMNAKCNJ1SMN1; SMN2HTT | |
| SCHEMBL8897735 | 0.80 | SMN1; SMN2 (0.57) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL4188852 | 0.78 | LMNA (0.50) | ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL2719072 | 0.78 | POLB (0.67) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL25546222 | 0.78 | ALDH1A1 (0.55) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL15919361 | 0.78 | NPC1 (0.58) | ALDH1A1LMNAMAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |