Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 3/20 | 1.00 |
| ▸ | PRMT5 | O14744 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | PLAU | P00749 | 4/20 | 0.58 |
| ▸ | PLG | P00747 | 1/20 | 0.58 |
| ▸ | PLAT | P00750 | 1/20 | 0.58 |
| ▸ | KLK1 | P06870 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MASP2 | O00187 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 7/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 6/20 | 0.52 |
| ▸ | F12 | P00748 | 1/20 | 0.52 |
| ▸ | F7 | P08709 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stilbamidine SCHEMBL208655 | 1.00 | PRMT1 (1.00) | PRMT1PRMT5ALDH1A1HPGDCYP2C19 | |
| Stilbamidine SCHEMBL3932459 | 0.97 | PRMT1 (0.95) | PRMT1PRMT5ALDH1A1HPGDCYP2C19 | |
| Stilbamidine SCHEMBL871695 | 0.95 | PRMT1 (0.91) | PRMT1PRMT5ALDH1A1HPGDCYP2C19 | |
| SCHEMBL428474 | 0.91 | PRMT1 (0.83) | PRMT1PRMT5ALDH1A1HPGDCYP2C19 | |
| SCHEMBL428473 | 0.91 | PRMT1 (0.83) | PRMT1PRMT5ALDH1A1HPGDCYP2C19 | |
| Hydrochloric Acid SCHEMBL11333159 | 0.89 | PRMT1 (0.79) | PRMT1PRMT5ALDH1A1HPGDCYP2C19 | |
| Hydrochloric Acid SCHEMBL11333164 | 0.89 | PRMT1 (0.79) | PRMT1PRMT5ALDH1A1HPGDCYP2C19 | |
| SCHEMBL2521983 | 0.89 | PRMT1 (0.79) | PRMT1PRMT5ALDH1A1HPGDCYP2C19 | |
| SCHEMBL23902148 | 0.87 | PRMT1 (0.76) | PRMT1PRMT5ALDH1A1HPGDCYP2C19 | |
| SCHEMBL2520059 | 0.85 | ALDH1A1 (0.73) | PRMT1PRMT5ALDH1A1HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7310284-A | — | — | None | — | — | JP | disclosed |
| US-8465921-B2 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | ELITECH HOLDING B.V. (NL) | 2013-06-18 | — | — | US | disclosed |
| US-8465921-B2 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | ELITECH HOLDING B.V. (NL) | 2013-06-18 | — | — | US | disclosed |
| US-20110275070-A1 | HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS | EPOCH PHARMACEUTICALS, INC. | 2011-11-10 | — | — | US | disclosed |
| US-7794945-B2 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | ELITECH HOLDING B.V. (NL) | 2010-09-14 | — | — | US | disclosed |
| US-7556923-B1 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | EPOCH BIOSCIENCES, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-20090048427-A1 | HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS | EPOCH BIOSCIENCES, INC. (US) | 2009-02-19 | — | — | US | disclosed |
| US-7297495-B2 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES, INC. (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297495-B2 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES, INC. (US) | 2007-11-20 | — | — | US | disclosed |
| US-20070166723-A1 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES INC. (US) | 2007-07-19 | — | — | US | disclosed |
| US-20070166723-A1 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES INC. (US) | 2007-07-19 | — | — | US | disclosed |
| US-7163961-B1 | Drugs, foods and oral compositions containing stilbene-type compounds | SUNSTAR INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| EP-1161944-A1 | DRUGS, FOODS AND ORAL COMPOSITIONS CONTAINING STILBENE-TYPE COMPOUNDS | Sunstar Inc. (JP) | 2001-12-12 | — | — | EP | disclosed |
| JP-H07310284-A | ANTIMICROBIAL FIBROUS STRUCTURE | TORAY IND INC | 1995-11-28 | — | — | JP | disclosed |
| US-4716905-A | Method of retrograde fluorescent labeling of neurons | FLUOROCHROME, INC. (US) | 1988-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070166723-A1 | Hybridization-triggered fluorescent detection of nucleic acids | DDX21, RNGTT, NOP2 | PRMT1 4600/4885PRMT5 4481/4885ALDH1A1 3480/4885 |
| US-20090048427-A1 | HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS | DDB1, LIG3, MSH2 | PRMT1 4037/4885PRMT5 3830/4885ALDH1A1 4598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.