SCHEMBL8897900

SCHEMBL8897900

CN(C)C(C)(Cc1ccccc1)C(=O)c1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
ALDH1A1 P00352 2/20 0.44
ACHE P22303 4/20 0.43
ELANE P08246 2/20 0.42
SRD5A2 P31213 2/20 0.42
MLYCD O95822 1/20 0.42
PPARG P37231 1/20 0.40
BCHE P06276 1/20 0.40
PPARA Q07869 1/20 0.40
MMP8 P22894 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3322033 0.97 HPGD (0.47) HPGDNPC1RAB9AALDH1A1ACHE
SCHEMBL8899299 0.94 KMT2A (0.42) NPC1RAB9AALDH1A1MLYCDSMN1; SMN2
SCHEMBL8897425 0.88 KMT2A (0.41) HPGDNPC1RAB9AALDH1A1ACHE
SCHEMBL8898785 0.87 KMT2A (0.54) HPGDNPC1RAB9AALDH1A1MLYCD
SCHEMBL2697072 0.87 MLYCD (0.44) NPC1RAB9AALDH1A1MLYCDSMN1; SMN2
SCHEMBL8898280 0.85 NPC1 (0.44) HPGDNPC1RAB9ASRD5A2SMN1; SMN2
SCHEMBL23805930 0.84 SRD5A2 (0.42) HPGDNPC1RAB9AACHEELANE
SCHEMBL8897074 0.84 TDP1 (0.43) HPGDRAB9AALDH1A1MLYCDMMP8
SCHEMBL8896901 0.84 PPARG (0.46) HPGDRAB9AALDH1A1PPARGPPARA
SCHEMBL8899384 0.84 GPR52 (0.40) HPGDNPC1RAB9AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5629356-A PHOTOCURABLE COMPOSITION CONTAINING ETHYLENICALLY UNSATURATED PHOTOPOLYMERIZABLE COMPOUND AND THE AMINOACETOPHENONE CIBA GEIGY CORPORATION (US) 1997-05-13 US disclosed
US-5554663-A α-aminoacetophenones as photoinitiators CIBA-GEIGY CORPORATION (US) 1996-09-10 US disclosed
US-5534629-A PHOTOPOLYMERIZATION OF PIGMENTED SYSTEMS, INKS CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed
EP-0284561-B1 ALPHA-AMINOACETOPHENONES AS PHOTO INITIATORS CIBA-GEIGY AG (CH) 1993-05-12 EP disclosed
US-5077402-A For photocuring pigmented systems; printing inks, lacquers CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
EP-0284561-A2 Alpha-aminoacetophenones as photo initiators CIBA-GEIGY AG (CH) 1988-09-28 EP disclosed