Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.33 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.33 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788944 | 0.74 | KCNH3 (0.38) | KCNH3MAPTGAASIGMAR1S1PR2 | |
| SCHEMBL11666346 | 0.66 | GAA (0.33) | KCNH3MAPTGAASIGMAR1KDM4E | |
| SCHEMBL7328852 | 0.65 | MAPT (0.50) | MAPTGAALMNASMN1; SMN2RAB9A | |
| SCHEMBL4792080 | 0.65 | MAPT (0.41) | MAPTGAALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL30890804 | 0.65 | MAPT (0.41) | MAPTGAASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL1724131 | 0.65 | L3MBTL1 (0.51) | KCNH3MAPTGAASIGMAR1S1PR2 | |
| SCHEMBL8535750 | 0.63 | L3MBTL1 (0.54) | KCNH3MAPTSIGMAR1S1PR2LMNA | |
| SCHEMBL9390020 | 0.63 | MAPT (0.52) | MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL96273 | 0.63 | ALDH1A1 (0.70) | KCNH3MAPTSIGMAR1S1PR2LMNA | |
| SCHEMBL11266466 | 0.63 | L3MBTL1 (0.54) | KCNH3MAPTSIGMAR1S1PR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696111-A | ANTIARRHYTHMIC AGENTS | MERCK & CO., INC. (US) | 1997-12-09 | — | — | US | disclosed |