Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 13/20 | 0.46 |
| ▸ | FLT3 | P36888 | 3/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890072 | 0.94 | POLB (0.51) | VCPFLT3ADRA2ANPY5RPOLB | |
| SCHEMBL8890197 | 0.90 | PDE5A (0.48) | VCPADRA2ANPY5RAPPACHE | |
| SCHEMBL8898707 | 0.87 | FLT3 (0.48) | FLT3ADRA2ANPY5RAPPACHE | |
| SCHEMBL8899135 | 0.87 | TRIM58 (0.53) | VCPFLT3ADRA2ANPY5RPOLB | |
| SCHEMBL8898260 | 0.86 | VCP (0.50) | VCPAPPACHE | |
| SCHEMBL8901739 | 0.86 | TAAR1 (0.52) | VCPAPPACHEPOLB | |
| SCHEMBL8898351 | 0.85 | VCP (0.48) | VCPAPPACHE | |
| SCHEMBL8899747 | 0.84 | VCP (0.47) | VCP | |
| SCHEMBL8889919 | 0.84 | VCP (0.52) | VCP | |
| SCHEMBL8889077 | 0.83 | VCP (0.47) | VCPAPPACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |