Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811267 | 0.81 | CYP3A4 (0.40) | GPBAR1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8898970 | 0.76 | GPBAR1 (0.38) | GPBAR1L3MBTL1POLBKMT2APAX8 | |
| SCHEMBL11410673 | 0.69 | TSPO (0.45) | GPBAR1L3MBTL1POLBNPSR1PAX8 | |
| SCHEMBL7811272 | 0.67 | CDK8 (0.40) | GPBAR1KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL6529361 | 0.66 | ESR1 (0.46) | GPBAR1L3MBTL1POLBKMT2AMEN1 | |
| SCHEMBL6973685 | 0.65 | MEN1 (0.47) | KMT2AMEN1 | |
| SCHEMBL7824932 | 0.65 | TSPO (0.44) | GPBAR1L3MBTL1POLBNPSR1PAX8 | |
| SCHEMBL27397133 | 0.64 | MEN1 (0.43) | GPBAR1L3MBTL1POLBHTTNPSR1 | |
| SCHEMBL13233265 | 0.64 | L3MBTL1 (0.41) | GPBAR1L3MBTL1POLBALDH1A1RAB9A | |
| SCHEMBL9955764 | 0.63 | TSPO (0.47) | GPBAR1L3MBTL1POLBPAX8TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691362-A | ANTIHISTAMINES, BRONCHODILATORS, ANTIINFLAMMATORY AGENTS, GASTROINTESTINAL DISORDERS | SCHERING-PLOUGH CORPORATION (US) | 1997-11-25 | — | — | US | disclosed |