Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27415579 | 0.81 | MEN1 (0.65) | MEN1KMT2ACRHBPCRHR2ALDH1A1 | |
| SCHEMBL27416258 | 0.81 | LMNA (0.43) | MEN1KMT2AL3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL27398401 | 0.80 | LMNA (0.36) | SLC6A2SLC6A4ALDH1A1HPGD | |
| SCHEMBL27430310 | 0.77 | DRD4 (0.43) | MEN1KMT2AL3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL27396374 | 0.74 | ACHE (0.47) | MEN1KMT2ACRHBPCRHR2ALDH1A1 | |
| SCHEMBL28399460 | 0.72 | TSPO (0.46) | MEN1KMT2ACRHBPCRHR2L3MBTL1 | |
| SCHEMBL7811272 | 0.72 | CDK8 (0.40) | MEN1KMT2AALDH1A1GPBAR1 | |
| SCHEMBL27416257 | 0.72 | MEN1 (0.49) | MEN1KMT2AALDH1A1HPGDPOLB | |
| SCHEMBL27415578 | 0.72 | MLYCD (0.45) | MEN1KMT2A | |
| SCHEMBL20264683 | 0.71 | ALDH1A1 (0.51) | MEN1KMT2ACRHBPCRHR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1085661-C | Piperidine derivatives as neurokinin antagonists | SCHERING CORP (US) | 2002-05-29 | — | — | CN | disclosed |
| CN-1161033-A | Piperidine derivatives as neurokinin antagonists | SCHERING CORP (US) | 1997-10-01 | — | — | CN | disclosed |