Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2166950 | 0.93 | ATM (0.37) | HCAR2THRBAKR1B10AKR1B1ALOX5 | |
| SCHEMBL230779 | 0.89 | HCAR2 (0.39) | HCAR2THRBAKR1B10AKR1B1ALOX5 | |
| SCHEMBL230551 | 0.88 | HCAR2 (0.38) | HCAR2THRBAKR1B10AKR1B1ALOX5 | |
| SCHEMBL852400 | 0.88 | HCAR2 (0.38) | HCAR2THRBAKR1B10AKR1B1ALOX5 | |
| SCHEMBL8899017 | 0.83 | THRB (0.59) | HCAR2THRBAKR1B10AKR1B1L3MBTL1 | |
| SCHEMBL17287255 | 0.80 | HCAR2 (0.41) | HCAR2AKR1B10AKR1B1ALOX5ATM | |
| SCHEMBL17373023 | 0.80 | HCAR2 (0.41) | HCAR2AKR1B10AKR1B1ALOX5ATM | |
| SCHEMBL10629493 | 0.80 | HCAR2 (0.41) | HCAR2AKR1B10AKR1B1ALOX5ATM | |
| SCHEMBL4623580 | 0.79 | HCAR2 (0.40) | HCAR2AKR1B10AKR1B1ALOX5ATM | |
| SCHEMBL22092326 | 0.79 | HCAR2 (0.40) | HCAR2AKR1B10AKR1B1ALOX5ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700874-A | CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE | BRIDGESTONE CORPORATION (JP) | 1997-12-23 | — | — | US | disclosed |