SCHEMBL8899294

SCHEMBL8899294

CC(N)C1Cc2cc(C#N)ccc2O1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PNMT P11086 5/20 0.37
ABCB1 P08183 8/20 0.36
KDM1A O60341 1/20 0.36
DPP4 P27487 2/20 0.34
DRD2 P14416 1/20 0.33
DRD3 P35462 1/20 0.33
PTGS2 P35354 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8042044 0.78 AKT1 (0.35)
SCHEMBL8039833 0.77 PNMT (0.39) PNMTKDM1A
SCHEMBL8688431 0.76 TDP1 (0.51) PNMTABCB1DRD2DRD3
SCHEMBL8038143 0.73 CYP19A1 (0.43)
SCHEMBL8042053 0.73 CYP19A1 (0.43)
SCHEMBL8038148 0.73 CYP19A1 (0.43)
SCHEMBL8042060 0.73 CYP19A1 (0.43)
SCHEMBL8036024 0.73 CYP19A1 (0.43)
SCHEMBL2152307 0.71 PNMT (0.35) PNMTABCB1KDM1ADPP4PTGS2
SCHEMBL8035992 0.71 PNMT (0.45) PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587110-B1 Condensed heterocyclic derivatives and agricultural or horticultural fungicides containing the same KUMIAI CHEMICAL INDUSTRY CO (JP) 1997-12-17 EP disclosed
US-5348976-A Amide derivatives as fungicides safe for plants KUMAI CHEMICAL INDUSTRY CO., LTD. (JP) 1994-09-20 US disclosed
EP-0587110-A2 Condensed heterocyclic derivatives and agricultural or horticultural fungicides containing the same KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1994-03-16 EP disclosed