Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 13/20 | 0.46 |
| ▸ | F2 | P00734 | 7/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898242 | 0.89 | F7 (0.45) | F7F2F10CA12CA1 | |
| SCHEMBL4413240 | 0.87 | F7 (0.44) | F7F2F10CA12CA1 | |
| SCHEMBL8898015 | 0.84 | F7 (0.47) | F7F2MAPTNAMPT | |
| SCHEMBL4426386 | 0.78 | F7 (0.64) | F7F2F10ITGB3 | |
| SCHEMBL29951995 | 0.77 | MAPT (0.64) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8896780 | 0.76 | F7 (0.41) | F7F2F10CA12CA1 | |
| SCHEMBL1514347 | 0.76 | RAB9A (0.68) | CASRMAPT | |
| SCHEMBL4417206 | 0.75 | PPID (0.47) | F7CA12CA1CA2CA9 | |
| SCHEMBL16223190 | 0.74 | NAMPT (0.69) | ALDH1A1CASRMAPTNAMPT | |
| SCHEMBL20335100 | 0.74 | ALDH1A1 (0.71) | ALDH1A1ITGB3ITGB1ITGAVITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703050-A | INHIBIT PLATELET AGGREGATION, METASTASIS OF CARCINOMA CELLS, OSTEOCLAST BINDING TO BONE SURFACE | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |