Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MASP2 | O00187 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899533 | 0.84 | F7 (0.46) | F7MAPTNAMPTF2 | |
| SCHEMBL8381984 | 0.81 | KDM1A (0.47) | MAPTNAMPTPOLBKMT2AGAA | |
| SCHEMBL6658849 | 0.80 | RAB9A (0.47) | POLBKMT2AGAARAB9AMASP2 | |
| SCHEMBL10942377 | 0.80 | LMNA (0.59) | POLBKMT2ARAB9AMASP2MEN1 | |
| SCHEMBL5845871 | 0.80 | NR4A1 (0.51) | POLBKMT2ARAB9AMASP2LMNA | |
| SCHEMBL2771354 | 0.79 | ENPP2 (0.52) | KMT2AMASP2F2LMNAHTT | |
| SCHEMBL8898242 | 0.79 | F7 (0.45) | F7F2 | |
| SCHEMBL7450597 | 0.79 | CTRB1 (0.49) | POLBKMT2ARAB9AMASP2F2 | |
| SCHEMBL7300740 | 0.78 | MAPT (0.52) | MAPTKMT2AMASP2TP53MEN1 | |
| SCHEMBL4413240 | 0.78 | F7 (0.44) | F7F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703050-A | INHIBIT PLATELET AGGREGATION, METASTASIS OF CARCINOMA CELLS, OSTEOCLAST BINDING TO BONE SURFACE | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |