Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 16/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890529 | 0.91 | TGFBR1 (0.53) | TGFBR1KDM4EPKMNPY5R | |
| SCHEMBL27917809 | 0.85 | NPY5R (0.58) | NPY5RNPY1RMAPT | |
| SCHEMBL14834135 | 0.84 | MGLL (0.64) | TGFBR1NPY5RNPY1RMAPT | |
| SCHEMBL14695860 | 0.84 | TGFBR1 (0.79) | TGFBR1KDM4EPKM | |
| SCHEMBL6039411 | 0.83 | ACACB (0.69) | NPY5RNPY1RMAPT | |
| SCHEMBL6039406 | 0.83 | ACACB (0.69) | NPY5RNPY1RMAPT | |
| SCHEMBL10194489 | 0.82 | ACACB (0.71) | TGFBR1 | |
| SCHEMBL8899558 | 0.81 | ACKR3 (0.53) | NPY5RNPY1R | |
| SCHEMBL8899052 | 0.79 | NPY5R (0.55) | TGFBR1NPY5RNPY1RMAPT | |
| SCHEMBL8899046 | 0.79 | NPY5R (0.55) | TGFBR1NPY5RNPY1RMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020820-A1 | HETEROARYL COMPOUNDS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |