Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 11/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 2/20 | 0.48 |
| ▸ | CCR8 | P51685 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899787 | 0.91 | TGFBR1 (0.64) | TGFBR1KDM4EPKMNPY5R | |
| SCHEMBL8899558 | 0.84 | ACKR3 (0.53) | HTR6NPY5R | |
| SCHEMBL6347374 | 0.82 | SLC6A9 (0.51) | NPY5R | |
| SCHEMBL16112711 | 0.78 | KDM4E (0.58) | TGFBR1KDM4EPKMSTSGPR119 | |
| SCHEMBL8901280 | 0.78 | TGFBR1 (0.64) | TGFBR1KDM4EPKMSTS | |
| SCHEMBL27900155 | 0.77 | SCN1A (0.49) | KDM4ENPY5R | |
| SCHEMBL4266289 | 0.77 | CNR1 (0.59) | KDM4EHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13932868 | 0.76 | HTR2A (0.52) | STSGPR119 | |
| SCHEMBL2459419 | 0.75 | KDM4E (0.52) | TGFBR1KDM4EPKMHTR6GPR119 | |
| SCHEMBL14834135 | 0.75 | MGLL (0.64) | TGFBR1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020820-A1 | HETEROARYL COMPOUNDS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |