Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.49 |
| ▸ | NPY1R | P25929 | 7/20 | 0.49 |
| ▸ | HTR7 | P34969 | 5/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900712 | 0.85 | HTR7 (0.54) | NPY5RNPY1RHTR7HTR6HTR1A | |
| SCHEMBL8890529 | 0.84 | TGFBR1 (0.53) | NPY5RHTR6 | |
| SCHEMBL12502091 | 0.82 | CCR1 (0.58) | NPY5RHTR7HTR6HTR1ACCR1 | |
| SCHEMBL8899787 | 0.81 | TGFBR1 (0.64) | NPY5RNPY1R | |
| SCHEMBL8899046 | 0.79 | NPY5R (0.55) | NPY5RNPY1R | |
| SCHEMBL8899052 | 0.79 | NPY5R (0.55) | NPY5RNPY1R | |
| SCHEMBL19764641 | 0.79 | RORC (0.71) | — | |
| SCHEMBL12204590 | 0.78 | MEN1 (0.64) | ACKR3HTR7HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL11101542 | 0.78 | ALOX15 (0.64) | NPY5RNPY1RHTR7HTR6HTR1A | |
| SCHEMBL18889424 | 0.78 | ACHE (0.56) | ACKR3CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020820-A1 | HETEROARYL COMPOUNDS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |