Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 15/20 | 0.59 |
| ▸ | NPC1 | O15118 | 13/20 | 0.59 |
| ▸ | RAB9A | P51151 | 12/20 | 0.59 |
| ▸ | MAPT | P10636 | 9/20 | 0.59 |
| ▸ | TP53 | P04637 | 8/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.57 |
| ▸ | RELA | Q04206 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CASP3 | P42574 | 2/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890246 | 0.83 | POLB (0.61) | POLBSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8891089 | 0.81 | MAPT (0.68) | SMN1; SMN2MAPTTP53HTTALDH1A1 | |
| SCHEMBL8901242 | 0.80 | LMNA (0.60) | POLBSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8898815 | 0.80 | TSHR (0.59) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL15474905 | 0.77 | ALDH1A1 (0.61) | SMN1; SMN2NPC1RAB9AMAPTHTT | |
| SCHEMBL8890668 | 0.74 | PDE4D (0.57) | POLBSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL1224760 | 0.72 | ALDH1A1 (0.62) | SMN1; SMN2NPC1RAB9AMAPTHTT | |
| SCHEMBL4025388 | 0.72 | ALDH1A1 (0.51) | POLBSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL3925449 | 0.72 | NPSR1 (0.54) | POLBSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL4109085 | 0.72 | NPC1 (0.80) | SMN1; SMN2NPC1RAB9AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |