Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 16/20 | 0.68 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 6/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898815 | 0.90 | TSHR (0.59) | MAPTTP53TSHRMEN1KMT2A | |
| SCHEMBL8890753 | 0.83 | MAPT (0.68) | MAPTTP53TSHRNPY1RNPY2R | |
| SCHEMBL8899801 | 0.81 | POLB (0.61) | MAPTTP53TSHRMEN1KMT2A | |
| SCHEMBL8901242 | 0.80 | LMNA (0.60) | MAPTTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL11887851 | 0.76 | MAPT (0.78) | MAPTTP53TSHRNPY1RNPY2R | |
| SCHEMBL3397230 | 0.76 | PDCD1 (0.67) | MAPTTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL14597978 | 0.74 | RAB9A (0.78) | MAPTTSHRNPY1RNPY2RMEN1 | |
| SCHEMBL8889628 | 0.74 | PDE4D (0.61) | MAPTTP53TSHRNPY1RNPY2R | |
| SCHEMBL8892213 | 0.73 | MAPT (0.58) | MAPTTP53TSHRMEN1KMT2A | |
| SCHEMBL8899857 | 0.73 | MAPT (0.58) | MAPTTP53TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |