Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 9/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.57 |
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.57 |
| ▸ | RELA | Q04206 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900264 | 0.84 | LMNA (0.60) | LMNATSHRRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8902534 | 0.83 | LMNA (0.59) | LMNATSHRRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8899801 | 0.80 | POLB (0.61) | LMNATSHRRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8891089 | 0.80 | MAPT (0.68) | LMNATSHRSMN1; SMN2MAPTKMT2A | |
| SCHEMBL8898815 | 0.79 | TSHR (0.59) | LMNATSHRRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8900644 | 0.75 | PDE4D (0.56) | LMNATSHRRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2705643 | 0.71 | RAB9A (0.57) | LMNATSHRRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL12728834 | 0.71 | RAB9A (0.63) | LMNATSHRRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL1300154 | 0.71 | HPGD (0.66) | LMNATSHRRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5937486 | 0.70 | ERN1 (0.59) | TSHRNPC1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |