Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 5/20 | 0.33 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899885 | 0.84 | AKT1 (0.40) | AKT1DNMT3BHSP90AA1PAX8 | |
| SCHEMBL8531494 | 0.68 | DNMT3B (0.53) | AKT1DNMT3BHSP90AA1PAX8 | |
| SCHEMBL8531103 | 0.66 | DNMT3B (0.48) | AKT1DNMT3BHSP90AA1PAX8 | |
| SCHEMBL8900149 | 0.63 | AKT1 (0.34) | AKT1 | |
| SCHEMBL8587198 | 0.62 | TCF4 (0.39) | AKT1DNMT3BHSP90AA1PAX8 | |
| SCHEMBL8900155 | 0.61 | AKT1 (0.47) | AKT1 | |
| SCHEMBL9755762 | 0.60 | HTT (0.34) | — | |
| SCHEMBL8900228 | 0.60 | TCF4 (0.39) | AKT1DNMT3BHSP90AA1PAX8 | |
| SCHEMBL8899620 | 0.58 | AKT1 (0.50) | AKT1DNMT3BHSP90AA1PAX8 | |
| SCHEMBL8907639 | 0.57 | CTH (0.38) | AKT1DNMT3BHSP90AA1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5606037-A | Processes antineoplastic heteronaphthoquinones | BIOCHEM PHARMA INC. (CA) | 1997-02-25 | — | — | US | claimed |
| EP-0659190-A1 | ANTINEOPLASTIC HETERONAPHTHOQUINONES | BIOCHEM PHARMA INC (CA) | 1995-06-28 | — | — | EP | claimed |
| WO-1994011382-A1 | ANTINEOPLASTIC HETERONAPHTHOQUINONES | BIOCHEM PHARMA INC. (CA) | 1994-05-26 | — | — | WO | claimed |
| US-5606037-A | Processes antineoplastic heteronaphthoquinones | BIOCHEM PHARMA INC. (CA) | 1997-02-25 | — | — | US | disclosed |
| EP-0659190-A1 | ANTINEOPLASTIC HETERONAPHTHOQUINONES | BIOCHEM PHARMA INC (CA) | 1995-06-28 | — | — | EP | disclosed |
| WO-1994011382-A1 | ANTINEOPLASTIC HETERONAPHTHOQUINONES | BIOCHEM PHARMA INC. (CA) | 1994-05-26 | — | — | WO | disclosed |