Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900155 | 0.82 | AKT1 (0.47) | AKT1PRKACA | |
| SCHEMBL9755793 | 0.80 | NQO1 (0.32) | — | |
| SCHEMBL8902037 | 0.71 | AKT1 (0.44) | AKT1 | |
| SCHEMBL8900948 | 0.68 | AKT1 (0.42) | AKT1PRKACA | |
| SCHEMBL8528779 | 0.66 | AKT1 (0.42) | AKT1 | |
| SCHEMBL31237790 | 0.65 | AKT1 (0.49) | AKT1PRKACA | |
| SCHEMBL9755794 | 0.64 | NQO1 (0.42) | AKT1 | |
| SCHEMBL8899879 | 0.63 | AKT1 (0.33) | AKT1 | |
| SCHEMBL9755756 | 0.63 | SMN1; SMN2 (0.40) | AKT1 | |
| SCHEMBL9755757 | 0.63 | MAPT (0.41) | AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5606037-A | Processes antineoplastic heteronaphthoquinones | BIOCHEM PHARMA INC. (CA) | 1997-02-25 | — | — | US | claimed |
| US-5606037-A | Processes antineoplastic heteronaphthoquinones | BIOCHEM PHARMA INC. (CA) | 1997-02-25 | — | — | US | disclosed |
| EP-0659190-A1 | ANTINEOPLASTIC HETERONAPHTHOQUINONES | BIOCHEM PHARMA INC (CA) | 1995-06-28 | — | — | EP | disclosed |
| WO-1994011382-A1 | ANTINEOPLASTIC HETERONAPHTHOQUINONES | BIOCHEM PHARMA INC. (CA) | 1994-05-26 | — | — | WO | disclosed |