Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2585956 | 0.85 | CALM1 (0.43) | CALM1MAPTCYP3A4 | |
| SCHEMBL711973 | 0.83 | CALM1 (0.57) | CALM1IDO1MAPTCYP3A4ALDH1A1 | |
| SCHEMBL14740719 | 0.81 | PNMT (0.47) | SIGMAR1IDO1TAAR1CYP3A4AGXT | |
| SCHEMBL27739505 | 0.80 | CALM1 (0.37) | CALM1IDO1CYP3A4ALDH1A1 | |
| SCHEMBL27430888 | 0.80 | TP53 (0.44) | CALM1TAAR1MAPTHPGDHTT | |
| SCHEMBL2874671 | 0.80 | LMNA (0.37) | CALM1IDO1TAAR1KMT2AL3MBTL1 | |
| SCHEMBL27754324 | 0.80 | ALDH1A1 (0.44) | CALM1CYP3A4ALDH1A1 | |
| SCHEMBL9686662 | 0.80 | SRD5A2 (0.38) | CALM1IDO1TAAR1MEN1KMT2A | |
| SCHEMBL7911223 | 0.80 | ESR1 (0.56) | SIGMAR1CALM1IDO1TAAR1HIF1A | |
| SCHEMBL3033555 | 0.79 | IGF1R (0.43) | TAAR1ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684205-A | CHLORIDE CHANNEL BLOCKERS FOR CONTROLLING AIRWAY DISEASES, SECRETORY DIARRHEA AND ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-11-04 | — | — | US | claimed |
| EP-0701988-A1 | Substituted cyclopentane-di- and triones, their preparation and their use as chloride channel blockers | BAYER AG (DE) | 1996-03-20 | — | — | EP | claimed |
| US-5684205-A | CHLORIDE CHANNEL BLOCKERS FOR CONTROLLING AIRWAY DISEASES, SECRETORY DIARRHEA AND ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-11-04 | — | — | US | disclosed |
| EP-0701988-A1 | Substituted cyclopentane-di- and triones, their preparation and their use as chloride channel blockers | BAYER AG (DE) | 1996-03-20 | — | — | EP | disclosed |
| CN-1091425-A | Heterocyclic neophenan analogs, process for their preparation and their use as pesticides | HOECHST AG (DE) | 1994-08-31 | — | — | CN | disclosed |
| EP-0288810-B1 | HETEROCYCLIC NEOPHANE ANALOGS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-02 | — | — | EP | disclosed |
| US-5116826-A | SILAZANEOPHYL SULFIDES, AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |
| CN-1050878-A | Novel silane derivs contains the preparation of this derivative and as the application of agricultural chemicals | HOECHST AG (DE) | 1991-04-24 | — | — | CN | disclosed |
| US-5002957-A | Insecticides, acaricides, nematocides | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-26 | — | — | US | disclosed |
| US-4990621-A | Insecticides, miticides and nematocides; 3-(3-fluoro-4-phenoxyphenyl, 3-(5-fluoro-3-phenoxypyrid-2-yl) or 3-(3-methyl-4-phenyl prop-1-ene | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| US-4966902-A | INSECTICIDES, MITICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-30 | — | — | US | disclosed |
| EP-0249015-B1 | SILANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM, AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-27 | — | — | EP | disclosed |
| EP-0224024-B1 | SILANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-20 | — | — | EP | disclosed |
| CN-1036570-A | The new silylation sulfide of new alkyl sulfur compounds of azepine and azepine, they the preparation method, contain their preparation and they are as the application of sterilant | HOECHST AG (DE) | 1989-10-25 | — | — | CN | disclosed |
| EP-0336199-A1 | Azaneophyl and silazaneophyl sulfides, process for their preparation, agents containing them, and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-11 | — | — | EP | disclosed |
| US-4864027-A | INSECTICIDES, NEMATOCIDES, MITICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0288810-A1 | Heterocyclic neophane analogs, processes for their preparation and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-02 | — | — | EP | disclosed |
| US-4775664-A | INSECTICIDES, MITICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-04 | — | — | US | disclosed |
| EP-0249015-A1 | Silane derivatives, process for their preparation, agents containing them, and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-16 | — | — | EP | disclosed |
| EP-0224024-A1 | Silane derivatives, process for their preparation, agents containing them and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-06-03 | — | — | EP | disclosed |