Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | PTPRF | P10586 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 3/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 6/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11613036 | 0.81 | MEN1 (0.50) | POLBALDH1A1SCN1ASCN2ASCN3A | |
| SCHEMBL28339381 | 0.74 | CHRNA7 (0.56) | PTPN2PTPN1PTPRFTSHRSCN1A | |
| SCHEMBL8837565 | 0.74 | PTPN2 (0.42) | POLBPTPN2PTPN1PTPRFALDH1A1 | |
| SCHEMBL9386746 | 0.74 | BCHE (0.51) | POLBPTPN2PTPN1ALDH1A1LMNA | |
| SCHEMBL8837627 | 0.74 | CA1 (0.56) | POLBPTPN2PTPN1PTPRFALDH1A1 | |
| SCHEMBL9026170 | 0.72 | SCN1A (0.40) | POLBPTPN2PTPN1PTPRFALDH1A1 | |
| SCHEMBL9387290 | 0.71 | ATM (0.42) | POLBPTPN2PTPN1PTPRFALDH1A1 | |
| SCHEMBL20562753 | 0.70 | PTPN1 (0.46) | PTPN2PTPN1PTPRFPTPN6PTPN11 | |
| SCHEMBL756511 | 0.70 | POLB (0.64) | POLBALDH1A1HSD17B10KDM4ETSHR | |
| SCHEMBL30096217 | 0.70 | POLB (0.64) | POLBALDH1A1HSD17B10KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003980-A1 | SUBSTITUTED ARYL SULPHONYL AMINO (THIO) CARBONYL TRIAZOLIN(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-06 | — | — | WO | disclosed |