Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.60 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935279 | 0.76 | DRD2 (0.50) | DRD2DRD3ADRA1A | |
| SCHEMBL8169648 | 0.75 | HTR1A (1.00) | HTR1ADRD2DRD3DRD4 | |
| SCHEMBL8169645 | 0.75 | HTR1A (1.00) | HTR1ADRD2DRD3DRD4 | |
| SCHEMBL5167242 | 0.70 | HTR1A (0.89) | HTR1ADRD2DRD3DRD4 | |
| SCHEMBL5171727 | 0.70 | HTR1A (0.89) | HTR1ADRD2DRD3DRD4 | |
| SCHEMBL5167251 | 0.70 | HTR1A (0.89) | HTR1ADRD2DRD3DRD4 | |
| SCHEMBL5171731 | 0.70 | HTR1A (0.89) | HTR1ADRD2DRD3DRD4 | |
| SCHEMBL10760426 | 0.68 | HTR1A (0.84) | HTR1ADRD2DRD3DRD4 | |
| SCHEMBL10760431 | 0.68 | HTR1A (0.84) | HTR1ADRD2DRD3DRD4 | |
| SCHEMBL10760422 | 0.68 | HTR1A (0.84) | HTR1ADRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482084-B1 | (1,2N) AND (3,2N)-CARBOCYCLIC-2-AMINO TETRALIN DERIVATIVES | UPJOHN CO (US) | 1997-05-07 | — | — | EP | claimed |