SCHEMBL8900552

SCHEMBL8900552

COP(=O)(C(=O)C(C)(C)C)c1ccc(C)cc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.44
TSHR P16473 2/20 0.44
HPGD P15428 2/20 0.41
GAA P10253 3/20 0.41
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 3/20 0.34
CYP3A4 P08684 1/20 0.34
RAB9A P51151 2/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
TP53 P04637 1/20 0.33
NPC1 O15118 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57751 0.84 POLB (0.43) LMNATSHRHPGDGAATDP1
SCHEMBL3242585 0.75 LMNA (0.40) LMNATSHRHPGDGAATDP1
SCHEMBL11206435 0.72 CES2 (0.47) LMNATSHRHPGDGAATDP1
SCHEMBL58133 0.69 CES2 (0.47) LMNAGAATDP1MEN1MAPT
SCHEMBL22229025 0.68 HPGD (0.45) LMNATSHRHPGDGAATDP1
SCHEMBL384926 0.68 HPGD (0.54) LMNATSHRHPGDGAATDP1
SCHEMBL3895562 0.68 HPGD (0.54) LMNATSHRHPGDGAATDP1
SCHEMBL5483761 0.66 HPGD (0.58) LMNATSHRHPGDGAATDP1
SCHEMBL10237191 0.65 HPGD (0.50) LMNATSHRHPGDGAATDP1
P-Xylene SCHEMBL28167985 0.64 ALDH1A1 (0.50) LMNATSHRHPGDGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11945891-B2 Speaker having an adhesive composition DENKA COMPANY LIMITED (JP) 2024-04-02 US disclosed
US-20200231726-A1 COMPOSITION DENKA COMPANY LIMITED (JP) 2020-07-23 US disclosed
US-5698285-A PHOTOCURABLE THREE BOND CO., LTD. (JP) 1997-12-16 US disclosed
EP-0007508-B1 ACYLPHOSPHINOXIDE COMPOUNDS, THEIR PREPARATION AND THEIR USE BASF Aktiengesellschaft (DE) 1983-06-01 EP disclosed
US-4324744-A PHOTOINITIATORS BASF AKTIENGESELLSCHAFT (DE) 1982-04-13 US disclosed
EP-0007508-A2 Acylphosphinoxide compounds, their preparation and their use BASF Aktiengesellschaft (DE) 1980-02-06 EP disclosed