Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900621 | 0.85 | NPSR1 (0.50) | ALDH1A1NPSR1CYP3A4TDP1KMT2A | |
| SCHEMBL2231821 | 0.76 | NPSR1 (0.52) | CALM1ALDH1A1NPSR1CYP3A4TSHR | |
| SCHEMBL8614123 | 0.73 | ALDH1A1 (0.73) | CALM1ALDH1A1NPSR1CYP3A4TSHR | |
| SCHEMBL14018354 | 0.72 | CALM1 (0.55) | CALM1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL9768685 | 0.72 | CALM1 (0.55) | CALM1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL27463137 | 0.72 | LMNA (0.56) | CALM1ALDH1A1NPSR1CYP3A4TSHR | |
| SCHEMBL473162 | 0.70 | NPSR1 (0.55) | CALM1ALDH1A1NPSR1CYP3A4TSHR | |
| SCHEMBL23992505 | 0.70 | CALM1 (0.60) | CALM1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL3162196 | 0.70 | CALM1 (0.60) | CALM1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL22942241 | 0.68 | ESR1 (0.58) | CALM1ALDH1A1CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973735-B1 | POLYAROMATIC ANTIVIRAL COMPOSITIONS | UPJOHN CO (US) | 2003-01-29 | — | — | EP | claimed |