Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.56 |
| ▸ | PDE4A | P27815 | 3/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.56 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890634 | 0.85 | PDE4D (0.60) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL8900252 | 0.84 | PDE4D (0.65) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL8890668 | 0.84 | PDE4D (0.57) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL8889628 | 0.84 | PDE4D (0.61) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL8902534 | 0.83 | LMNA (0.59) | MAPTPKMLMNATSHRSMN1; SMN2 | |
| SCHEMBL8900264 | 0.82 | LMNA (0.60) | MAPTPKMLMNATSHRSMN1; SMN2 | |
| SCHEMBL8890135 | 0.80 | PDE4B (0.70) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL8889614 | 0.77 | PDE4D (0.73) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL8888686 | 0.77 | PDE4D (0.73) | PDE4DPDE4BPDE4APDE4CCYP2B6 | |
| SCHEMBL8888975 | 0.75 | PDE4D (0.70) | PDE4DPDE4BPDE4APDE4CCYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | claimed |