Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.60 |
| ▸ | PDE4A | P27815 | 2/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.59 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.58 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889628 | 0.94 | PDE4D (0.61) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL8890864 | 0.90 | THRB (0.51) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL8900252 | 0.87 | PDE4D (0.65) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL8901320 | 0.87 | PDE4D (0.56) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL8890668 | 0.85 | PDE4D (0.57) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL8900644 | 0.85 | PDE4D (0.56) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL8899650 | 0.84 | PDE4D (0.60) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL8892213 | 0.83 | MAPT (0.58) | SMPD1MAPTTP53THRBGSTP1 | |
| SCHEMBL8899857 | 0.83 | MAPT (0.58) | SMPD1MAPTTP53THRBGSTP1 | |
| SCHEMBL8898765 | 0.83 | ALOX15 (0.65) | PDE4DPDE4APDE4BPDE4CCYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | claimed |
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |