Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 15/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | AQP1 | P29972 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | NPY4R | P50391 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898270 | 0.87 | VCP (0.54) | VCPNPY5RSLC6A4 | |
| SCHEMBL8900660 | 0.85 | ADRB2 (0.51) | NPY5RADRA2AMCHR1ADRB2SLC6A4 | |
| SCHEMBL8900961 | 0.84 | VCP (0.56) | VCPNPY5RSLC6A4 | |
| SCHEMBL2636279 | 0.84 | NPY5R (0.61) | VCPNPY5RADRA2AMCHR1SLC6A4 | |
| Hydrochloric Acid SCHEMBL2675355 | 0.83 | NPY5R (0.60) | VCPNPY5RADRA2AMCHR1SLC6A4 | |
| SCHEMBL8892672 | 0.78 | NPY5R (0.56) | VCPNPY5RADRA2AMCHR1SLC6A4 | |
| SCHEMBL8919888 | 0.74 | NPY5R (0.61) | NPY5RADRA2AMCHR1SLC6A4ALDH1A1 | |
| SCHEMBL8889919 | 0.72 | VCP (0.52) | VCP | |
| SCHEMBL8901212 | 0.72 | VCP (0.54) | VCPNPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL3947713 | 0.72 | ADRA2A (0.69) | VCPNPY5RADRA2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |