Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634459 | 0.91 | CHRM5 (0.40) | CHRM5CHRM1CHRM3KMT2AALDH1A1 | |
| SCHEMBL8630909 | 0.87 | HSD17B10 (0.37) | CHRM5CHRM1CHRM3KMT2AALDH1A1 | |
| SCHEMBL8900831 | 0.82 | CHRM1 (0.42) | CHRM5CHRM1CHRM3RBP4MALT1 | |
| SCHEMBL8901086 | 0.74 | CHRM1 (0.40) | CHRM5CHRM1CHRM3KMT2AALDH1A1 | |
| SCHEMBL4684270 | 0.71 | AVPR2 (0.41) | CHRM5CHRM1CHRM3KMT2AALDH1A1 | |
| SCHEMBL8632028 | 0.71 | GRM4 (0.41) | CHRM5CHRM1CHRM3KMT2AALDH1A1 | |
| SCHEMBL4743947 | 0.71 | GRM4 (0.39) | CHRM5CHRM1CHRM3KMT2AALDH1A1 | |
| SCHEMBL8631926 | 0.71 | AVPR2 (0.44) | CHRM5CHRM1CHRM3KMT2AALDH1A1 | |
| SCHEMBL4684937 | 0.70 | AVPR2 (0.50) | CHRM5CHRM1CHRM3GRM4HTR1A | |
| SCHEMBL8632058 | 0.70 | ALDH1A1 (0.43) | CHRM5CHRM1CHRM3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |