Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898796 | 0.93 | P2RX7 (0.46) | CYSLTR2CYSLTR1P2RX7KDM4EALDH1A1 | |
| SCHEMBL8901046 | 0.83 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL8998153 | 0.80 | EPHX2 (0.66) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL10368754 | 0.79 | EPHX2 (0.65) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL9479238 | 0.75 | AAK1 (0.47) | CYSLTR2CYSLTR1EPHX2NR1H4KDM4E | |
| SCHEMBL8951214 | 0.73 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL8998286 | 0.73 | EPHX2 (0.56) | CYSLTR2CYSLTR1EPHX2NR1H4KDM4E | |
| SCHEMBL10368401 | 0.73 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1 | |
| SCHEMBL9478047 | 0.72 | AGTR1 (0.47) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL24812989 | 0.72 | ALDH1A1 (0.52) | CYSLTR2CYSLTR1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997005114-A1 | QUINOLONE SULFONIMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-02-13 | — | — | WO | disclosed |