SCHEMBL8901065

SCHEMBL8901065

Nc1ccc(-c2ccc(N)cc2-c2ccc(CO)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.39
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
TSHR P16473 2/20 0.39
GFER P55789 1/20 0.39
FYN P06241 2/20 0.39
TP53 P04637 2/20 0.39
CYP19A1 P11511 2/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
CYP17A1 P05093 1/20 0.37
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
PDK2 Q15119 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
KIF11 P52732 1/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.36
PSEN1 P49768 1/20 0.36
PSEN2 P49810 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30880329 0.85 ALDH1A1 (0.53) CYP3A4ALDH1A1TDP1TSHRTP53
SCHEMBL14110641 0.85 ALDH1A1 (0.53) CYP3A4ALDH1A1TDP1TSHRTP53
SCHEMBL6572296 0.84 FYN (0.39) CYP3A4ALDH1A1TDP1TSHRGFER
SCHEMBL27660026 0.84 LOXL2 (0.60) CYP3A4ALDH1A1TDP1TSHRGFER
SCHEMBL1309905 0.83 CYP3A4 (0.58) CYP3A4ALDH1A1TDP1TSHRGFER
SCHEMBL28349056 0.80 ALDH1A1 (0.53) CYP3A4ALDH1A1TDP1TSHRTP53
SCHEMBL3784988 0.80 CYP3A4 (0.39) CYP3A4ALDH1A1TDP1TSHRGFER
SCHEMBL54121 0.80
SCHEMBL9505452 0.79 HSD17B10 (0.56) CYP3A4ALDH1A1TDP1TP53CA12
SCHEMBL29141132 0.79 HSD17B10 (0.56) CYP3A4ALDH1A1TDP1TP53CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5639581-A ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI XEROX CO., LTD. (JP) 1997-06-17 US disclosed