Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.54 |
| ▸ | TFEB | P19484 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242510 | 0.92 | NFE2L2 (0.62) | KDM4EHPGDHSD17B10NFE2L2TFEB | |
| SCHEMBL1665178 | 0.89 | HPGD (0.58) | KDM4EHPGDHSD17B10NFE2L2TFEB | |
| SCHEMBL26667032 | 0.88 | GAA (0.60) | KDM4EHPGDHSD17B10NFE2L2TFEB | |
| SCHEMBL8900889 | 0.87 | NFE2L2 (0.49) | KDM4EHPGDHSD17B10NFE2L2TFEB | |
| SCHEMBL7542596 | 0.85 | KDM4E (0.54) | KDM4EHPGDHSD17B10NFE2L2TFEB | |
| SCHEMBL8901624 | 0.84 | NFE2L2 (0.59) | KDM4EHPGDHSD17B10NFE2L2MAPT | |
| SCHEMBL8900072 | 0.84 | NFE2L2 (0.59) | KDM4EHPGDHSD17B10NFE2L2MAPT | |
| SCHEMBL11925422 | 0.83 | KDM4E (0.70) | KDM4EHPGDHSD17B10MAPTNPC1 | |
| SCHEMBL31312540 | 0.82 | NFE2L2 (0.52) | KDM4EHPGDNFE2L2TFEBMAPT | |
| SCHEMBL14775180 | 0.81 | NFE2L2 (0.49) | KDM4EHPGDHSD17B10NFE2L2TFEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663391-B1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | HOFFMANN LA ROCHE (CH) | 1997-04-09 | — | — | EP | disclosed |
| EP-0663391-A1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-19 | — | — | EP | disclosed |