Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.62 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.46 |
| ▸ | TFEB | P19484 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901347 | 0.92 | KDM4E (0.58) | NFE2L2TRPA1KDM4EHPGDHSD17B10 | |
| SCHEMBL8900889 | 0.89 | NFE2L2 (0.49) | NFE2L2TRPA1KDM4EHPGDHSD17B10 | |
| SCHEMBL8901624 | 0.86 | NFE2L2 (0.59) | NFE2L2TRPA1KDM4EHPGDHSD17B10 | |
| SCHEMBL8900072 | 0.86 | NFE2L2 (0.59) | NFE2L2TRPA1KDM4EHPGDHSD17B10 | |
| SCHEMBL26667032 | 0.84 | GAA (0.60) | NFE2L2TRPA1KDM4EHPGDHSD17B10 | |
| SCHEMBL4982109 | 0.83 | NFE2L2 (0.61) | NFE2L2TRPA1KDM4EHPGDHSD17B10 | |
| SCHEMBL4982103 | 0.83 | NFE2L2 (0.61) | NFE2L2TRPA1KDM4EHPGDHSD17B10 | |
| SCHEMBL9244563 | 0.83 | NFE2L2 (0.59) | NFE2L2TRPA1KDM4ECYP1A1CYP1A2 | |
| SCHEMBL1665178 | 0.81 | HPGD (0.58) | NFE2L2KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL12095299 | 0.79 | NFE2L2 (0.51) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438052-A | Cephalosporin derivatives | HOFFMANN-LA ROCHE INC. (US) | 1995-08-01 | — | — | US | disclosed |