Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900072 | 1.00 | NFE2L2 (0.59) | NFE2L2CYP1A1CYP1A2CYP1B1MAOB | |
| SCHEMBL8902315 | 0.87 | RELA (0.51) | NFE2L2MAOBCYP19A1KDM4EJAK2 | |
| SCHEMBL8900320 | 0.87 | RELA (0.51) | NFE2L2MAOBCYP19A1KDM4EJAK2 | |
| SCHEMBL9242510 | 0.86 | NFE2L2 (0.62) | NFE2L2CYP1A1CYP1A2CYP1B1TRPA1 | |
| SCHEMBL8900889 | 0.85 | NFE2L2 (0.49) | NFE2L2CYP1A1CYP1A2CYP1B1TRPA1 | |
| SCHEMBL8901347 | 0.84 | KDM4E (0.58) | NFE2L2MAOBNR1H3TRPA1KDM4E | |
| SCHEMBL8901021 | 0.82 | NFE2L2 (0.56) | NFE2L2CYP1A1CYP1A2CYP1B1MAOB | |
| SCHEMBL8902293 | 0.82 | NFE2L2 (0.56) | NFE2L2CYP1A1CYP1A2CYP1B1MAOB | |
| SCHEMBL8899878 | 0.81 | RELA (0.58) | NFE2L2CYP1A1CYP1A2CYP1B1MAOB | |
| SCHEMBL8900736 | 0.81 | RELA (0.58) | NFE2L2CYP1A1CYP1A2CYP1B1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663391-B1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | HOFFMANN LA ROCHE (CH) | 1997-04-09 | — | — | EP | disclosed |
| EP-0663391-A1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-19 | — | — | EP | disclosed |