Malonic Acid

Malonic Acid

SCHEMBL8901505

CCC=C(CC)OCC.O=C(O)CC(=O)O

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
CYP2D6 P10635 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
SOAT1 P35610 1/20 0.38
EGLN1 Q9GZT9 1/20 0.37
HCAR2 Q8TDS4 1/20 0.36
LDHA P00338 1/20 0.36
SRR Q9GZT4 1/20 0.36
FFAR3 O14843 1/20 0.35
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ALOX15 P16050 1/20 0.33
NPSR1 Q6W5P4 1/20 0.31
GLO1 Q04760 1/20 0.31
TRPA1 O75762 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21847430 0.72 ALDH1A1 (0.47) ALDH1A1CYP2D6SMN1; SMN2MGAMGAA
SCHEMBL704215 0.72 FFAR3 (0.36) ALDH1A1FFAR3
SCHEMBL3555076 0.70 HCAR2 (0.46) ALDH1A1CYP2D6SMN1; SMN2MGAMGAA
SCHEMBL9838210 0.69 NPSR1 (0.50) ALDH1A1CYP2D6SMN1; SMN2MGAMGAA
SCHEMBL27365507 0.69 MGAM (0.45) ALDH1A1MGAMGAASIMGAM2
Malonic Acid Diethyl Ester SCHEMBL8406575 0.69 GAA (0.79) ALDH1A1CYP2D6SMN1; SMN2MGAMGAA
Malonic Acid Diethyl Ester SCHEMBL18911581 0.69 GAA (0.79) ALDH1A1CYP2D6SMN1; SMN2MGAMGAA
SCHEMBL704834 0.69 SOAT1 (0.36) ALDH1A1SOAT1FFAR3
SCHEMBL11142045 0.68 DGAT1 (0.33) GAALDHASRRMEN1KMT2A
SCHEMBL12282126 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0799052-A1 NEW ANTITHROMBOTIC FORMULATION, PROCESS FOR ITS MANUFACTURING, AND USE THEREOF Astra Aktiebolag (SE) 1997-10-08 EP disclosed
WO-1996016671-A1 NEW ANTITHROMBOTIC FORMULATION, PROCESS FOR ITS MANUFACTURING, AND USE THEREOF ASTRA AKTIEBOLAG (SE) 1996-06-06 WO disclosed
US-5053507-A Liquid crystal dopants ARAKAWA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-10-01 US disclosed