Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8527872 | 0.81 | ADRA1A (0.40) | ADRA1ACYP1A2ACHEALDH1A1HPGD | |
| SCHEMBL8530160 | 0.79 | ADRA1A (0.38) | ADRA1ACYP1A2ACHEALDH1A1HPGD | |
| SCHEMBL8529815 | 0.79 | ADRA1A (0.46) | ADRA1ACYP1A2ACHEALDH1A1HPGD | |
| SCHEMBL8527470 | 0.78 | CYP1A2 (0.47) | ADRA1ACYP1A2ACHEALDH1A1HPGD | |
| SCHEMBL8527137 | 0.78 | MIF (0.45) | ADRA1ACYP1A2ACHEALDH1A1HPGD | |
| SCHEMBL8527142 | 0.76 | MIF (0.46) | ADRA1ACYP1A2ACHEALDH1A1HPGD | |
| SCHEMBL8901644 | 0.75 | CTDSP1 (0.44) | ADRA1ACYP1A2ALDH1A1HPGD | |
| SCHEMBL8531328 | 0.74 | ADRA1A (0.41) | ADRA1ACYP1A2ACHEALDH1A1HPGD | |
| SCHEMBL8901566 | 0.73 | — | — | |
| SCHEMBL8533392 | 0.72 | ADRA1A (0.42) | ADRA1ACYP1A2ACHEALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |
| WO-1991019725-A2 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1991-12-26 | — | — | WO | disclosed |