Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1645816 | 0.86 | EGFR (0.43) | HCRTR1HCRTR2MEN1KMT2ADRD2 | |
| Hydrochloric Acid SCHEMBL8471990 | 0.83 | HCRTR1 (0.35) | HPGDHCRTR1HCRTR2KDM4EALDH1A1 | |
| SCHEMBL17513586 | 0.81 | TSHR (0.38) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8472064 | 0.73 | DRD2 (0.44) | NPC1LMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL22462980 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1 | |
| SCHEMBL9273128 | 0.70 | CHRNB2 (0.53) | SMN1; SMN2 | |
| SCHEMBL22463000 | 0.70 | HTR2A (0.37) | MEN1KMT2ADRD2 | |
| SCHEMBL7812867 | 0.67 | CHRNB2 (0.52) | DRD2SLC6A4 | |
| SCHEMBL28748573 | 0.66 | CHRNA7 (0.44) | HCRTR1HCRTR2ALDH1A1SLC6A4GAA | |
| SCHEMBL4259594 | 0.62 | CYP2A6 (0.48) | NPC1LMNATP53RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997040010-A1 | HALOGENATED NAPHTHYL METHOXY PIPERIDINES FOR MAPPING SEROTONIN TRANSPORTER SITES | EMORY UNIVERSITY (US) | 1997-10-30 | — | — | WO | disclosed |