Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.43 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.37 |
| ▸ | PPIG | Q13427 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901685 | 0.86 | NPC1 (0.40) | DRD2SLC6A4MEN1KMT2AHCRTR1 | |
| Hydrochloric Acid SCHEMBL8471990 | 0.85 | HCRTR1 (0.35) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL7812867 | 0.80 | CHRNB2 (0.52) | EGFRERBB2DRD2SLC6A4HRH3 | |
| SCHEMBL17513586 | 0.77 | TSHR (0.38) | — | |
| SCHEMBL9273128 | 0.74 | CHRNB2 (0.53) | — | |
| SCHEMBL22462980 | 0.74 | KDM4E (0.47) | — | |
| SCHEMBL10681131 | 0.73 | EGFR (0.41) | EGFRERBB2DRD2SLC6A4KDM1A | |
| SCHEMBL24774496 | 0.72 | DRD2 (0.43) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL10377064 | 0.72 | SIGMAR1 (0.41) | EGFRERBB2DRD2SLC6A4KDM1A | |
| SCHEMBL28748573 | 0.70 | CHRNA7 (0.44) | SLC6A4HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110097274-A1 | Carbon-11 and fluorine-18 labeled radioligands for positron emission tomography (PET) imaging for the brain serotonin transporters | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-04-28 | — | — | US | disclosed |
| EP-1519917-A4 | CARBON-11 AND FLUORINE-18 LABELED RADIOLIGANDS FOR POSITRON EMISSION TOMOGRAPHY (PET) IMAGING FOR THE BRAIN SEROTONIN TRANSPORTERS | UNIV COLUMBIA (US) | 2006-05-17 | — | — | EP | disclosed |
| EP-1519917-A2 | CARBON-11 AND FLUORINE-18 LABELED RADIOLIGANDS FOR POSITRON EMISSION TOMOGRAPHY (PET) IMAGING FOR THE BRAIN SEROTONIN TRANSPORTERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2005-04-06 | — | — | EP | disclosed |
| WO-2003096978-A2 | CARBON-11 AND FLUORINE-18 LABELED RADIOLIGANDS FOR POSITRON EMISSION TOMOGRAPHY (PET) IMAGING FOR THE BRAIN SEROTONIN TRANSPORTERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2003-11-27 | — | — | WO | disclosed |
| US-5919797-A | DIAGNOSIS, THERAPY PSYCHOLOGICAL DISORDERS | EMORY UNIVERSITY (US) | 1999-07-06 | — | — | US | disclosed |
| US-5919797-A | DIAGNOSIS, THERAPY PSYCHOLOGICAL DISORDERS | EMORY UNIVERSITY (US) | 1999-07-06 | — | — | US | disclosed |
| US-5919797-A | DIAGNOSIS, THERAPY PSYCHOLOGICAL DISORDERS | EMORY UNIVERSITY (US) | 1999-07-06 | — | — | US | disclosed |
| WO-1997040010-A1 | HALOGENATED NAPHTHYL METHOXY PIPERIDINES FOR MAPPING SEROTONIN TRANSPORTER SITES | EMORY UNIVERSITY (US) | 1997-10-30 | — | — | WO | disclosed |
| WO-1997040010-A1 | HALOGENATED NAPHTHYL METHOXY PIPERIDINES FOR MAPPING SEROTONIN TRANSPORTER SITES | EMORY UNIVERSITY (US) | 1997-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110097274-A1 | Carbon-11 and fluorine-18 labeled radioligands for positron emission tomography (PET) imaging for the brain serotonin transporters | SLC6A4, SLC18A2, SLC6A2 | EGFR 1505/4885ERBB2 3478/4885ERBB3 3454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.