Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903531 | 0.90 | NR1D1 (0.33) | KDM4ENPC1PKMRAB9AADORA3 | |
| SCHEMBL8901799 | 0.87 | NQO1 (0.37) | KDM4EALDH1A1POLBMAPTRECQL | |
| SCHEMBL8903519 | 0.86 | NR1D1 (0.33) | KDM4ENPC1PKMRAB9AADORA3 | |
| SCHEMBL8903221 | 0.86 | NR1D1 (0.33) | KDM4ENPC1PKMRAB9AADORA3 | |
| SCHEMBL8902819 | 0.83 | KDM4E (0.34) | KDM4ENPC1PKMRAB9AADORA3 | |
| SCHEMBL8902587 | 0.83 | KDM4E (0.34) | KDM4ENPC1PKMRAB9AADORA3 | |
| SCHEMBL8903683 | 0.83 | NQO1 (0.37) | KDM4EALDH1A1POLBMAPTRECQL | |
| SCHEMBL8902939 | 0.83 | NQO1 (0.37) | KDM4EALDH1A1POLBMAPTRECQL | |
| SCHEMBL9522381 | 0.83 | KDM4E (0.34) | KDM4ENPC1PKMRAB9AADORA3 | |
| SCHEMBL8902595 | 0.81 | CTH (0.36) | KDM4ENPC1PKMRAB9AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |