Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CTH | P32929 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903519 | 1.00 | NR1D1 (0.33) | NR1D1HTTALDH1A1KDM4EKMT2A | |
| SCHEMBL8903531 | 0.96 | NR1D1 (0.33) | NR1D1HTTALDH1A1KDM4EKMT2A | |
| SCHEMBL8901727 | 0.86 | KDM4E (0.34) | HTTALDH1A1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL8902600 | 0.84 | ALDH1A1 (0.35) | NR1D1HTTALDH1A1KDM4ETSHR | |
| SCHEMBL8902842 | 0.84 | ALDH1A1 (0.35) | NR1D1HTTALDH1A1KDM4ETSHR | |
| SCHEMBL9521733 | 0.83 | KDM4E (0.33) | HTTALDH1A1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL9755801 | 0.80 | KDM4E (0.34) | HTTALDH1A1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL8902603 | 0.80 | AKT1 (0.36) | ALDH1A1KDM4EKMT2AL3MBTL1CTH | |
| SCHEMBL8903173 | 0.80 | TSHR (0.34) | NR1D1HTTALDH1A1KDM4EKMT2A | |
| SCHEMBL8902823 | 0.79 | IDO1 (0.39) | HTTALDH1A1KDM4EKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |